The potential of lignolytic enzymes for oxidative polymer degradation.

At Delft University of Technology (The Netherlands) we coordinate the work on the scientific basics of the envisioned enzymatic polymer degradation. Inspired by nature’s solutions to degrade recalcitrant lignin, the research group investigates so-called peroxygenases to degrade non-natural polymers for which nature has not developed degradation strategies (yet). Natural enzymes and human-engineered enzymes are investigated [...]

2022-07-15T10:44:56+01:00July 15th, 2022|

Bizente Technology, transferred to stakeholders at ESOF 2022

  The Bizente project consortium is having quite a busy summer, participating in various international conferences and workshops. In July, for example, the strategic lines of Bizente were presented by Evoenzyme at the workshop "A sustainable future with sustainable plastics", organised by the project coordinator, Aitiip Centro Tecnológico. In addition to the technical presentation, in [...]

2022-07-15T10:16:22+01:00July 15th, 2022|

Engineering composite degrading enzymes by Directed Evolution

The role of EvoEnzyme in BIZENTE is to engineer the most promising composite degrading enzymes by Directed Evolution. During the last months we have been developing high-throughput screening assays to detect activity on model molecules from the resins (epoxy, vinyl-ester and polyester). These assays have allowed us to explore libraries in Saccharomyces cerevisiae and to [...]

2022-07-01T09:54:12+01:00July 1st, 2022|

Cured thermoset materials could finally be 100% chemically recycled

The objective of BIZENTE project (https://specificpolymers.com/bizente/) is to develop multi-step degradation process to degrade thermoset materials (cured reference resins used) at their end-of-life. To do so, BIZENTE partners are working in parallel in order to develop specific enzymes custom designed on the basis of reference resin and, on the other hand, achieve chemical modification of [...]

2022-06-15T10:02:17+01:00June 15th, 2022|

Interim report on exploitable results and IPR management

A Key Exploitable Result (KER) is an identified main interesting result which has been selected and prioritized due to its high potential to be "exploited". The objective of the Interim report on exploitable results and IPR management is to identify BIZENTE background, to determine the ownership of project’s results and to evaluate the best procedure [...]

2022-06-15T09:54:23+01:00June 15th, 2022|

Progresses in searching for resin chemical modifications able to ease the enzymatic degradation

The objective of BIZENTE project is to develop a multi-step degradation process to degrade thermoset materials at their end-of-life. To do so, BIZENTE partners are working in parallel in order to develop specific enzymes custom designed on the basis of reference resin and also to achieve chemical modification of the reference resins in order to [...]

2022-06-15T09:18:20+01:00June 15th, 2022|

Toxicity assessment in BIZENTE

Toxicity assessment is fundamental not only to guarantee the quality of a product and the safety of the process, but also from the point of view of environmental protection and the achievement of sustainable development objectives. For this reason, the University of Cadiz is studying the effects of the new, more biodegradable and sustainable products [...]

2022-06-06T08:45:26+01:00June 6th, 2022|

Lab scale trials on the enzymatic biodegradation of resins/composites

One of the main challenges that stand in front of our society is related to the economic structure and, in particular, these challenges embrace how to evolve the economy architecture from a linear system toward circular networks of feedstock and products. In this vision, a strong interconnection between the recycling of end-of-life products and production [...]

2022-06-06T08:28:51+01:00June 6th, 2022|

Issue 4, May 2022

BIZENTE NEWSLETTER Issue number 4, May 2022 BIZENTE: MOVING FORWARD BIZENTE keeps advancing! In the last 6 months, BIZENTE partners have been working hard and great advances were achieved. Novel enzymes have been successfully expressed, resins have been successfully modified and the first degradation tests have been carried out. The first steps towards the scaling [...]

2022-06-15T10:00:25+01:00May 10th, 2022|

Frank Hollmann: “BIZENTE opens up an important application for ligninases to contribute to a more sustainable Europe. It is exciting being part of such a bold endeavor”

Frank Hollmann studied Chemistry (University of Bonn, Germany) and received his PhD from the Swiss Federal University of Technology (ETH Zurich) in 2004 with Andreas Schmid and Bernard Witholt as promotors. After a postdoctoral stay with Manfred Reetz (Max-Planck Institute for Coal Research, Germany) and some years as R&D manager at Evonik Industries [...]

2022-05-10T08:36:24+01:00May 10th, 2022|