At Delft University of Technology (The Netherlands) we coordinate the work on the scientific basics of the envisioned enzymatic polymer degradation. Inspired by nature’s solutions to degrade recalcitrant lignin, the research group investigates so-called peroxygenases to degrade non-natural polymers for which nature has not developed degradation strategies (yet). Natural enzymes and human-engineered enzymes are investigated [...]

  The Bizente project consortium is having quite a busy summer, participating in various international conferences and workshops. In July, for example, the strategic lines of Bizente were presented by Evoenzyme at the workshop "A sustainable future with sustainable plastics", organised by the project coordinator, Aitiip Centro Tecnológico. In addition to the technical presentation, in [...]

The role of EvoEnzyme in BIZENTE is to engineer the most promising composite degrading enzymes by Directed Evolution. During the last months we have been developing high-throughput screening assays to detect activity on model molecules from the resins (epoxy, vinyl-ester and polyester). These assays have allowed us to explore libraries in Saccharomyces cerevisiae and to [...]

The objective of BIZENTE project (https://specificpolymers.com/bizente/) is to develop multi-step degradation process to degrade thermoset materials (cured reference resins used) at their end-of-life. To do so, BIZENTE partners are working in parallel in order to develop specific enzymes custom designed on the basis of reference resin and, on the other hand, achieve chemical modification of [...]

A Key Exploitable Result (KER) is an identified main interesting result which has been selected and prioritized due to its high potential to be "exploited". The objective of the Interim report on exploitable results and IPR management is to identify BIZENTE background, to determine the ownership of project’s results and to evaluate the best procedure [...]

The objective of BIZENTE project is to develop a multi-step degradation process to degrade thermoset materials at their end-of-life. To do so, BIZENTE partners are working in parallel in order to develop specific enzymes custom designed on the basis of reference resin and also to achieve chemical modification of the reference resins in order to [...]

Toxicity assessment is fundamental not only to guarantee the quality of a product and the safety of the process, but also from the point of view of environmental protection and the achievement of sustainable development objectives. For this reason, the University of Cadiz is studying the effects of the new, more biodegradable and sustainable products [...]

One of the main challenges that stand in front of our society is related to the economic structure and, in particular, these challenges embrace how to evolve the economy architecture from a linear system toward circular networks of feedstock and products. In this vision, a strong interconnection between the recycling of end-of-life products and production [...]

Frank Hollmann studied Chemistry (University of Bonn, Germany) and received his PhD from the Swiss Federal University of Technology (ETH Zurich) in 2004 with Andreas Schmid and Bernard Witholt as promotors. After a postdoctoral stay with Manfred Reetz (Max-Planck Institute for Coal Research, Germany) and some years as R&D manager at Evonik Industries [...]